Frequently Used Excipients in Solid Dosage Formulation


Excipients are well defined in the official pharmacopoeia. Here we mentioned a list of the most commonly used excipients in oral solid dosage formulation -

Diluent

Calcium carbonate, Calcium phosphate, Dibasic calcium phosphate, Tribasic calcium sulfate cellulose, Microcrystalline cellulose, Dextrates, Dextrin, Dextrose, Excipient, Fructose, Kaolin, Lacitol, Lactose, Mannitol, Sorbitol, Starch, Pregelatinized starch, Sugar, Compressible sugar, Confectioner's sugar etc.

Binder

Acacia, Alginic acid, Carboxymethyl cellulose, Sodium cellulose, Liquid guar gum, Hydroxypropyl methyl cellulose, Povidone k-30, Pregelatinized starch syrup etc.

Glidant

Calcium silicate, Magnesium silicate, Silicon dioxide, Colloidal talc etc.

Disintegrant

Alginic acid, Cellulose, Microcrystalline cellulose, Croscarmellose sodium, Cross povidone, Sodium starch glycolate, Pregelatinized starch etc.

Lubricant

Calcium stearate, Magnesium stearate, Mineral oil, Light PEG, Purified talc, Vegetable oil, Stearic acid etc.

Coating Agent

Carboxymethyl cellulose, Cellulose acetate, Cellulose acetate pthalate (CAP), Ethyl cellulose, Hydroxypropyl methylcellulose (HPMC), Hydroxypropyl methyl cellulose pthalate, Methacrylic acid copolymer, Methyl cellulose, PEG, Polyvinyl acetate, Shellac, Titanium dioxide, Wax, Carnauba wax, Microcrystalline zein etc..


Related Articles:

1 comment:

  1. Nice post! Please try to mention the percentage of excipients.

    ReplyDelete

Powered by Blogger.